OXYCODONE

Description

What is Oxycodone?

Buy Oxycodone Online – Oxycodone is the extended-release formulation of oxycodone. It is an opioid agonist available in 10 mg, 15 mg, 20 mg, 30 mg, 40 mg, 60 mg, and 80 mg of oxycodone hydrochloride for oral administration. Oxycodone is a derivation from thebaine, an opium alkaloid.

Oxycodone tablets also contain inactive ingredients, including hypromellose, butylated hydroxytoluene (BHT), polyethylene oxide, polyethylene glycol 400, titanium dioxide, and magnesium stearate.

Additionally, 10 mg tablets also contain hydroxypropyl cellulose, 15 mg contain yellow iron oxide, black iron oxide, and red iron oxide, 20 mg contain red iron oxide and polysorbate, 30 mg contain red iron oxide, black iron oxide, yellow iron oxide, and polysorbate 80, 40 mg contain yellow iron oxide and polysorbate 80, 60 mg contain black iron oxide, red iron oxide, and polysorbate 80, and 80 mg contain yellow iron oxide, hydroxypropyl cellulose, indigo carmine aluminum lake, and FD & C Blue No. #2.

Oxycodone is only for patients who need continuous long-term pain medication. It is not for “as needed” or for recreational use.

Oxycodone is an opioid pain medicine that is also available with the generic name Oxycodone. It belongs to the opioid analgesics category of drugs and helps relieve severe ongoing pain.

Oxycodone functions in the brain to change the feel and response of the body towards pain. You can take the higher strengths of Oxycodone only when you are taking moderate to large amounts of opioid pain medication.

Licit Uses of Oxycodone

One can buy Oxycodone online to manage severe pain that requires around-the-clock, daily, long-duration opioid treatment. Also, this medication is prescribed for pain, for which other treatment alternatives are inadequate.

FDA-approved Oxycodone for adults and opioid-tolerant pediatric patients of 11 years or above. People who are already taking and tolerating a minimum daily opioid (oxycodone or its equivalent) dosage of at least 20 mg orally.

As Oxycodone is an extended-release opioid medication, it has a higher risk of addiction, abuse, and misuse, even at recommended doses. It also has more significant risks of overdose and death. Due to these risk factors, doctors recommend Oxycodone only to those patients for whom other alternative treatment options such as non-opioid analgesics or immediate-release opioids are not tolerated, ineffective, or would be inadequate to provide required analgesic effects.

Illicit Uses of Oxycodone

Recent studies show an increase in the non-medical uses of Oxycodone in the United States. In a school survey of 7726 students from grades 7 to 12, over 1.3% of students reported continuous use of Oxycodone, and 1% reported drug use in the past year. Similar studies demonstrate that over 49% of adolescent abusers buy Oxycodone online for its euphoric effects.

Chemistry

Oxycodone contains oxycodone which derives its chemical name from codeine due to the similarities in the part of their chemical structure from the following differences:

• Oxycodone has a hydroxyl group attached at carbon-14, while codeine has hydrogen in its place
• Oxycodone has a 7,8-dihydro property, while codeine has a double bond between these carbons, and
• Like ketones, oxycodone has a carbonyl group attached in the area of a hydroxyl group as in codeine

Oxycodone is also similar to hydrocodone, the only difference being that it has a hydroxyl group linked to carbon-14.

Manufacturers market oxycodone as various salts, the most common of them is hydrochloride salt. The free base conversion ratios of different oxycodone salts are as follows:

• Hydrochloride: 0.896
• Bitartrate: 0.667
• Tartrate: 0.750
• Camphosulfonate: 0.567
• Pectinate: 0.588
• Phenylpropionate: 0.678
• Sulfate: 0.887
• Phosphate: 0.763
• Terephthalate: 0.792

The hydrochloride salt is the base of most oxycodone products in the United States.

Important Information

Oxycodone may make you drowsy or dizzy, and alcohol or marijuana can add to it. Avoid taking alcohol or any alcoholic beverages. Do not use heavy machinery, avoid driving, or do anything that requires alertness until you know the effect of this medicine on you.

Older adults, malnourished or debilitated people with chronic breathing disorders or wasting syndrome are more likely to face serious breathing problems.

Long-term use of opioid medications like Oxycodone may affect fertility in men or women, and they may lose the ability to have children. It is still unknown whether opioid effects on fertility are permanent or temporary.

What to know before taking Oxycodone?

Before taking Oxycodone, tell your medical healthcare provider if you are allergic to it or other opioid pain relievers such as oxymorphone or if you are going through other allergies. It may contain inactive ingredients, which can later cause allergic reactions or other health issues.

Before taking this medication, tell each of your medical healthcare providers about your medical history, especially of:

• Brain disorders such as a tumor, seizure (or convulsions), or head injury;
• Liver disease;
• Kidney disease;
• Breathing problems such as sleep apnea, asthma, COPD- chronic obstructive pulmonary disease;
• Mood swings or mental disorders such as depression, confusion;
• Stomach or intestinal blockage, constipation, paralytic ileus, diarrhea due to infection;
• Difficulty urinating;
• Difficulty swallowing;
• Gallbladder disease; or
• Pancreatitis

You should avoid taking Oxycodone during pregnancy. If you use Oxycodone during pregnancy, you could give birth to a drug-dependent baby. It can result in life-threatening withdrawal symptoms in the newborn baby. Opioid-dependent babies may need medical treatment for several weeks.

This drug passes into breast milk. If you are breastfeeding, ask the doctor before taking Oxycodone. Inform the doctor if you notice slow breathing or severe drowsiness in the nursing baby.

How to take Oxycodone?

Read the available medication guide before you start taking Oxycodone, and each time you get a refill. If you have any queries regarding how to take Oxycodone, you can consult your medical healthcare provider.

Take Oxycodone regularly as per your doctor’s directions, not as needed for breakthrough pain. Doctors recommend taking this drug with or without food, usually within every 12 hours. If you have nausea, your medical healthcare provider may consult you to take it with food. You may use other ways to decrease nausea, such as lying down for an hour or two with minimum possible head movements.

Swallow the whole tablet without crushing, chewing, breaking, or dissolving it because doing so can release all the drug in the body at a time leading to an increase in the risk of Oxycodone overdose.

To reduce the chance of choking or trouble swallowing tablets:

1. Take only one pill at a time if your dose is more than one pill.
2. Do not wet, lick, or pre-soak the tablet before placing it in your mouth.
3. Ensure to drink sufficient water to swallow it entirely.

Before you start taking this medication, ask your medical healthcare provider if you should start or stop taking other opioids. Other pain relievers like acetaminophen and ibuprofen can also be under prescription.

If you suddenly stop taking this medicine, you may face withdrawal symptoms such as:

• Trouble sleeping
• Anxiety
• Suicidal thoughts
• Nausea
• Runny nose
• Watering eyes
• Sweating
• Diarrhea
• Muscle aches
• Sudden changes in behavior

Oxycodone dosage

Your Oxycodone dosage will depend upon your age, the severity of your medical condition, your initial response to the treatment with Oxycodone, other medical conditions (if you have any), and other medications you take.

The usual initial dosage of Oxycodone for adults should be 10 mg within every 12 hours. Oxycodone is not under the recommendation for use by anyone younger than 11 years.

Overdose

In case of an overdose to Oxycodone, take medical help promptly or call the Poison helpline at 1-800-FDA-1088. An Oxycodone overdose can be deadly, especially in a child or someone taking it without a prescription. Overdose symptoms of Oxycodone may include slow breathing, severe drowsiness, pinpoint pupils, or no breathing.

What to avoid while using Oxycodone?

Avoid eating grapefruit or taking any grapefruit product in liquid form while using Oxycodone unless your medical healthcare provider says you may do so safely. Grapefruit can make an increment in the risk of side effects with this medicine.

Avoid consumption of alcohol because it can result in dangerous side effects, or death could occur. Also, avoid medication errors. Before buying Oxycodone, have a look at the brand and strength of Oxycodone you are putting into your cart.

Oxycodone side effects

Take instant medical help if you have an allergic reaction due to the use of Oxycodone. An allergic reaction sign may include trouble breathing, hives, swelling of your face, throat, lips, or tongue. Oxycodone’s common side effects may include headache, drowsiness, tiredness, dizziness, stomach pain, constipation, vomiting, and nausea.

Opioid medicines like Oxycodone can slow down or stop your breathing that may cause death. Your attendant or caregiver should give you naloxone and seek urgent medical attention if you have blue-colored lips, slow breathing with long pauses, or if you are hard to wake up.

Call your doctor immediately if you have:

• Weak pulse or slow heart rate;
• Shallow breathing, sighing, noisy breathing, breathing that stops during sleep;
• Seizure;
• A light-headed feeling;
• Unusual thoughts or behavior, confusion;
• High serotonin levels in the body- hallucinations, agitation, sweating, fever, rapid heart rate, shivering, twitching, muscle stiffness, nausea, loss of coordination, diarrhea, vomiting; or
• Low cortisol levels- vomiting, nausea, dizziness, loss of appetite, worsening weakness or tiredness

Keep in mind that it is not a complete list of possible side effects, and others may occur. For further information regarding side effects, consult your medical healthcare provider. 

The most common unwanted reactions that occurred due to Oxycodone include:

• Nausea
• Constipation
• Somnolence
• Pruritus
• Dizziness
• Headache
• Vomiting
• Sweating
• Asthenia

Other adverse effects of Oxycodone include:

Gastrointestinal disorders: diarrhea, abdominal pain, gastritis, dyspepsia

General conditions: fever, chills

Metabolic disorder: anorexia

Musculoskeletal disorder: muscle twitching

Psychiatric disorder: anxiety, abnormal dreams, dysphoria, confusion, insomnia, euphoria, unusual thoughts, nervousness

Respiratory disease: hiccups, dyspnea

Skin conditions: rash

Vascular disease: postural hypotension

Ear condition: tinnitus

Eye disorder: abnormal vision

Gastrointestinal diseases: eructation, increased appetite, stomatitis, dysphagia

General disease: edema, withdrawal symptoms, thirst, malaise, facial edema, chest pain

Oxycodone may increase the risks of severe reactions such as respiratory depression, respiratory arrest, apnea, hypotension, circulatory depression, or shock.

What drugs can interact with Oxycodone?

You may have withdrawal symptoms or breathing problems if you take certain other medicines. Tell your medical healthcare provider if you also use antifungal medication, antibiotics, seizure medication, blood pressure or heart treatment, or medicine to treat hepatitis C or HIV.

Oxycodone can interact with various other drugs and cause fatal side effects. Ensure that your doctor knows if you also use:

• Medicines for overactive bladder, irritable bowel syndrome, or motion sickness;
• Bronchodilator asthma or COPD (chronic obstructive pulmonary disease) medication, cold or allergy medicines, or a diuretic “water pill”;
• A sedative like Valium- Versed, Klonopin, Xanax, lorazepam, alprazolam, diazepam, and others;
• Other opioids- prescription cough medicine or opioid pain drug;
• Drugs that affect serotonin levels- a stimulant or medicine for nausea and vomiting, serious infections, migraine headaches, depression, or Parkinson’s disease;
• Drugs that cause sleepiness or slow down your breathing- medicine to treat mood changes or mental illness, a sleeping pill, a muscle relaxer.